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Karyopharm Therapeutics Inc. (KPTI) — benchmarks from SEC filings

Latest fiscal year 2025 · computed deterministically from XBRL 10-K data · coverage 100%

$146MRevenue FY2025
0.6%Revenue growth
-62.1%Operating margin
-134.2%Net margin
-51.6%FCF margin

In fiscal 2025, Karyopharm Therapeutics Inc. reported revenue of $146M, up 0.6% year over year. Operating margin was -62.1% and net margin -134.2%, on a free-cash-flow margin of -51.6% with capital expenditure at 0.0% of revenue. Every figure is computed directly from KPTI's SEC XBRL 10-K filing — deterministic, with no estimates.

Fiscal yearRevenueOp marginNet margin
FY2025$146M-62.1%-134.2%
FY2024$145M-82.2%-52.6%
FY2023$146M-88.7%-98.0%
FY2022$157M-90.5%-105.2%
FY2021$210M-46.8%-59.1%

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Source: SEC EDGAR XBRL (10-K filings), latest filed values. "n/a" = not disclosed under mapped tags — never estimated. Informational benchmarking, not investment advice. © CompsDesk / Sam Arora.