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IONIS PHARMACEUTICALS, INC. (IONS) — benchmarks from SEC filings

Latest fiscal year 2025 · computed deterministically from XBRL 10-K data · coverage 100%

$944MRevenue FY2025
33.8%Revenue growth
-40.4%Operating margin
-40.4%Net margin
-33.9%FCF margin

In fiscal 2025, IONIS PHARMACEUTICALS, INC. reported revenue of $944M, up 33.8% year over year. Operating margin was -40.4% and net margin -40.4%, on a free-cash-flow margin of -33.9% with capital expenditure at 5.5% of revenue. Every figure is computed directly from IONS's SEC XBRL 10-K filing — deterministic, with no estimates.

Fiscal yearRevenueOp marginNet margin
FY2025$944M-40.4%-40.4%
FY2024$705M-67.4%-64.4%
FY2023$788M-44.9%-46.5%
FY2022$587M-69.8%-45.9%
FY2021$810M-3.7%-3.5%

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Source: SEC EDGAR XBRL (10-K filings), latest filed values. "n/a" = not disclosed under mapped tags — never estimated. Informational benchmarking, not investment advice. © CompsDesk / Sam Arora.